4-Acetoxyindole → 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-4-yl acetate

HRID 1878884노트

반응식

HRID 1878884 반응식
Cl[C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8]([B:11]1[O:15][C:14]([CH3:17])([CH3:16])[C:13]([CH3:19])([CH3:18])[O:12]1)=[CH:7]2.[C:20]([O:23]C1C=CC=C2C=1C=CN2)(=[O:22])[CH3:21]>>[C:20]([O:23][C:5]1[CH:4]=[CH:3][CH:2]=[C:10]2[C:6]=1[CH:7]=[C:8]([B:11]1[O:15][C:14]([CH3:17])([CH3:16])[C:13]([CH3:19])([CH3:18])[O:12]1)[NH:9]2)(=[O:22])[CH3:21]

참가 물질

3

반응물 2

HCID 5839344-AcetoxyindoleHCID 532172117-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole

생성물 1

HCID 591331232-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-4-yl acetate

실험 절차

Prepared according to a procedure analogous to that described for 7-chloro-2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole using 1H-indol-4-yl acetate.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-94091b4b9911420e81b7ec361f9ea6e3
출처 데이터셋
uspto-grants-2012_11
특허 번호
US08314111B2

반응 노트

불러오는 중…