Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl chloroformate → Methyl 4-[2-fluoro-3-(methylthio)phenyl]piperazine-1-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl chloroformate | HCID 6586 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 1-[2-Fluoro-3-(methylthio)phenyl]piperazine | HCID 57448073 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Methyl 4-[2-fluoro-3-(methylthio)phenyl]piperazine-1-carboxylate | HCID 57448074 | — |
반응 단계
Preparation according to preparation 26: 1-[2-fluoro-3-(methylthio)phenyl]piperazine (1.25 g, 5.53 mmol), triethylamine (1.2 ml, 7.2 mmol), methylen chloride (50 ml), methyl chloroformate (0.49 g, 6.6 mmol). Yield: 1.56 g. MS m/z (rel. intensity, 70 eV) 284 (M+, 99), 196 (bp), 184 (44), 169 (54), 56 (60)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08314126B2 |
| 출처 데이터셋 | uspto-grants-2012_11 |
| ORD ID | ord-6bd1727f2cc3412e8cdf2942dc03a023 |
| 출처 메모 | uspto-grants-2012_11 |