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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1879057Generated: November 3, 2026

Methanol → HCID 57448076, compound

https://huagongshe.com/reaction/1879057

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantSodium MethoxideHCID 10942334—
ReactantHCID 57438788HCID 57438788—
SolventDimethylformamideHCID 6228—
ProductHCID 57448076HCID 57448076—

Reaction Steps

Preparation according to preparation 34: 4-[2-fluoro-3-(trifluoromethoxy)phenyl]piperidine (1.23 g, 4.7 mmol), N,N-dimethylformamide (20 ml), sodium methoxide in methanol (30%, 2.35 ml, 13.2 mmol). Yield: 1.32 g.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08314126B2
Source datasetuspto-grants-2012_11
ORD IDord-50975151c44e4c54aa14796e60b00232
Source noteuspto-grants-2012_11