Pyridinium chloride → HCID 57448054, compound

HRID 1879058Notes

Reaction equation

HRID 1879058 reaction equation
C[O:2][C:3]1[C:8]([O:9][C:10]([F:13])([F:12])[F:11])=[CH:7][CH:6]=[CH:5][C:4]=1[CH:14]1[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]1.Cl.N1C=CC=CC=1>>[NH:17]1[CH2:18][CH2:19][CH:14]([C:4]2[CH:5]=[CH:6][CH:7]=[C:8]([O:9][C:10]([F:12])([F:13])[F:11])[C:3]=2[OH:2])[CH2:15][CH2:16]1

Participants

3

Reactant 2

HCID 10176127Pyridinium chlorideHCID 57448076HCID 57448076, compound

Product 1

HCID 57448054HCID 57448054, compound

Procedure

Preparation according to Example 29: 4-[2-methoxy-3-(trifluoromethoxy)phenyl]piperidine (1.31 g, 4.7 mmol), pyridine hydrochloride (4 g). Yield: 0.5 g. MS m/z (relative intensity, 70 eV) 261 (M+, bp), 260 (31), 244 (11), 215 (6), 56 (93).

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-8d11742af4eb4d9bb391dcbdb42b4d71
Source dataset
uspto-grants-2012_11
Patent number
US08314126B2

Reaction notes

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