1-(Bromomethyl)-4-ethylbenzene → HCID 24951496, compound

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The title compound was prepared from 4-methyl-2-(2H-pyrazol-3-yl)-thiazole-5-carboxylic acid (pyridin-3-ylmethyl)-amide and 1-bromomethyl-4-ethyl-benzene as described in Example 49 and isolated as a white solid (0.056 g, 42 (% yield). 1H NMR (400 MHz, CDCl3) δ 8.61 (s, 1H), 8.52-8.58 (m, 1H), 7.72 (d, J=8 Hz, 1H), 7.06-7.48 (m, 6H), 6.80-6.84 (m, 1H), 6.08-6.15 (m, 1H), 4.63 (d, J=8 Hz, 2H), 2.75 (s, 3H), 2.61-2.70 (m, 2H), 1.13-1.26 (m, 3H); MS (M+H)+=418.2; Rt=1.38 min; HRMS (M+H)+=418.17.

Provenance & Evidence