N-Methylaniline → HCID 59489540, compound

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The title compound was prepared from methanesulfonic acid 2-(3-{4-methyl-5-[(pyridin-3-ylmethyl)-carbamoyl]-thiazol-2-yl}-pyrazol-1-yl)-ethyl ester and methyl-phenyl amine as describe in Example 77 and isolated as a white solid (0.043 g, 54% yield). 1H NMR (400 MHz, CDCl3) δ 8.63 (bs, 1H), 8.57 (d, J=4 Hz, 1H), 7.73 (d, J=8 Hz, 1H), 7.28-7.34 (m, 1H), 7.29 (d, J=2 Hz, 1H), 7.21-7.26 (m, 2H), 6.77 (d, J=2 Hz, 1H), 6.73 (t, J=8 Hz, 1H), 6.65 (d, J=8 Hz, 2H), 6.06-6.13 (bm, 2H), 4.64 (d, J=4 Hz, 2H), 4.34 (t, J=5 Hz, 2H), 3.83 (t, J=5 Hz, 2H), 2.76 (s, 3H), 2.74 (s, 3H); MS (M+H)+=432.9; Rt=1.28 min; HRMS (M+H)+=433.17.

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