Neophyl chloride → HCID 24955768, compound

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The title compound was prepared from 4-methyl-2-(2H-pyrazol-3-yl)thiazole-5-carboxylic acid 4-fluoro-benzylamide and (2-chloro-1,1-dimethyl-ethyl)-benzene as describe in Example 83 and isolated as a white solid (0.046 g, 33% yield). 1H NMR (400 MHz, CDCl3) δ 7.22-7.35 (m, 7H), 7.02-7.08 (m, 1H), 6.69 (d, J=2 Hz, 1H), 6.62 (d, J=2 Hz, 1H), 5.96-6.03 (bm, 1H), 4.57 (d, J=4 Hz, 2H), 4.28 (s, 2H), 2.73 (s, 3H), 1.40 (s, 6H); MS (M+H)+=449.2; Rt=1.64 min; HRMS (M+H)+=449.18.

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