HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58017467, compound → HCID 58017468, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58017467 | HCID 58017467 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 58017468 | HCID 58017468 | 99.5% |
Reaction Steps
To a solution of N-isoamyl-N-(3 Methoxyphenylsulfonyl)D-tert-leucine benzyl ester (2.0 g, 4.33 mmol) in MeOH (12 ml) is added 10% palladium on carbon (200 mg) and the reaction is stirred under ambient pressure of hydrogen for 4 hours. The reaction is filtered through celite and concentrated affording the title compound (1.6 g, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08314148B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-9475c6bbd15342339f6bbed0f3353b0e |
| Source note | uspto-grants-2012_11 |