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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 187942Generated: October 31, 2026

Tetrahydrofuran → tert-Butyl 4-(2-fluorophenyl)-4-hydroxypiperidine-1-carboxylate

https://huagongshe.com/reaction/187942

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant1-Bromo-2-fluorobenzeneHCID 61259—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
ReactantButyllithiumHCID 178418339—
Producttert-Butyl 4-(2-fluorophenyl)-4-hydroxypiperidine-1-carboxylateHCID 23566966—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-dc7d7873f5c648f3aaa6cf18d2c8bfc9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)