Hydrogen chloride-ethyl acetate → HCID 86653800, compound

Participants

Reaction Steps

A solution of ((S)-1-dimethylaminomethyl-3,3-dimethyl-butyl)-carbamic acid tert-butyl ester (1.6 g, 6.20 mmol, 1.0 equiv.) in dry HCl-ethyl acetate (31 mL) was stirred overnight at room temperature under nitrogen. Ethyl acetate was distilled off under reduced pressure to give crude (S)-4,4,N1,N1-tetramethyl-pentane-1,2-diamine hydrochloride salt (1.4 g) as a white solid.

Provenance & Evidence