Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Succinimidyl 3-(2-pyridyldithio)propionate → Spdp dtt
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Succinimidyl 3-(2-pyridyldithio)propionate | HCID 100682 | — |
| 반응물 | Succinimidyl 4-(N-maleimidomethyl)cyclohexanecarboxylate | HCID 125175 | — |
| 반응물 | D-1,4-Dithiothreitol | HCID 446094 | — |
| 생성물 | Spdp dtt | HCID 131730073 | — |
반응 단계
SPDP-modified/DTT-reduced streptavidin is mixed with SMCC-modified BLA (equimolar ratio) and allowed to react for 1-2 hrs RT (or overnight at 4 degrees). The streptavidin-BLA conjugate product is purified by gel filtration over P-60 resin.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08318450B2 |
| 출처 데이터셋 | uspto-grants-2012_11 |
| ORD ID | ord-140178af5867432dbe2b7afad34eb7ab |
| 출처 메모 | uspto-grants-2012_11 |