HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorodifluoroacetic acid → 4-Nitrosotetrahydro-2H-pyran-4-yl 2-chloro-2,2-difluoroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorodifluoroacetic acid | HCID 66154 | — |
| Reactant | N-(oxan-4-ylidene)hydroxylamine | HCID 12298558 | — |
| Reactant | HCID 178418268 | HCID 178418268 | — |
| Product | 4-Nitrosotetrahydro-2H-pyran-4-yl 2-chloro-2,2-difluoroacetate | HCID 44479142 | — |
Reaction Steps
4-Nitrosotetrahydro-2H-pyran-4-yl 2-chloro-2,2-difluoroacetate was prepared from tetrahydro-pyran-4-one oxime, lead tetraacetate and chlorodifluoroacetic acid using conditions of General Method 3. 1H NMR (360 MHz, chloroform-d) δ 4.06-4.23 (2H, m), 3.52-3.86 (2H, m), 2.27-2.70 (2H, m), 1.72-2.07 (2H, m).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08318705B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-7a6c5527225440c28a5f2f59810a2bd2 |
| Source note | uspto-grants-2012_11 |