反应详情

PEGA 1900 beads (300-500 μm, 0.24 mmol NH2/g) (4 g, 0.96 mmol ˜1 eq)) were treated with a 1:1 TBTU coupling mixture of FmocGlyOH (2 eq) and AllocGlyOH (2 eq), NEM (17 eq) and TBTU (3.8 eq). Coupling time was 3.5 h. Beads were washed 10× with DMF.

1. washBeads were washed 10× with DMF