HCID 59327113, compound → Tert-butyl 4-(2-(4-(ethoxycarbonyl)phenoxy)pyridin-3-YL)piperidine-1-carboxylate

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Reaction Steps

A mixture of tert-butyl 4-(2-(4-(ethoxycarbonyl)phenoxy)pyridin-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate (5.89 g, 13.87 mmol) and palladium hydroxide on carbon (0.950 g, 1.353 mmol) in EtOH (50 mL) was evacuated/purged with hydrogen (1 atm, 3×). After stirring at rt overnight. The mixture was filtered through a pad of Celite and the filtrate was concentrated to dryness to give a light-yellow oil. MS m/z: 427.1 [M+1].

Provenance & Evidence