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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1880288Generated: October 25, 2026

4-(1,3-Oxazol-5-yl)aniline → 2-((1R,2S)-2-aminocyclohexylamino)-4-(4-(oxazol-5-yl)phenylamino)pyrimidine-5-carboxamide

https://huagongshe.com/reaction/1880288

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(1,3-Oxazol-5-yl)anilineHCID 517747—
Reactant2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[4-(1,2-oxazol-5-yl)anilino]pyrimidine-5-carboxamideHCID 46184612—
Product2-((1R,2S)-2-aminocyclohexylamino)-4-(4-(oxazol-5-yl)phenylamino)pyrimidine-5-carboxamideHCID 46184136—

Reaction Steps

This compound was synthesised using the synthetic scheme described for the synthesis of compound 122, and using 4-(oxazol-5-yl)aniline in step 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318755B2
Source datasetuspto-grants-2012_11
ORD IDord-098fb7193adf41aa87ccf782e9816903
Source noteuspto-grants-2012_11