4-(2-Thienyl)aniline → HCID 46184607, compound

HRID 1880295Notes

Reaction equation

HRID 1880295 reaction equation
[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13]([NH:15][C:16]2[CH:21]=[CH:20][C:19]([C:22]3ON=[CH:24][CH:23]=3)=[CH:18][CH:17]=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1.[S:30]1C=CC=[C:31]1C1C=CC(N)=CC=1>>[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13]([NH:15][C:16]2[CH:17]=[CH:18][C:19]([C:22]3[S:30][CH:31]=[CH:24][CH:23]=3)=[CH:20][CH:21]=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1

Participants

3

Reactant 2

HCID 10724744-(2-Thienyl)anilineHCID 461846122-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[4-(1,2-oxazol-5-yl)anilino]pyrimidine-5-carboxamide

Product 1

HCID 46184607HCID 46184607, compound

Procedure

This compound was synthesised using the synthetic scheme described for the synthesis of compound 122, and using 4-(thiophen-2-yl)aniline in step 1. MS: 410.0 (M+H).

Workup

  1. customThis compound was synthesised

Sources & evidence

ORD record
ord-f4d79ba79b8b4fb8a6c0e5c1673231f9
Source dataset
uspto-grants-2012_11
Patent number
US08318755B2

Reaction notes

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