1-(3-Aminophenyl)pyrrolidin-2-one → 2-((1R,2S)-2-aminocyclohexylamino)-4-(3-(2-oxopyrrolidin-1-yl)phenylamino)pyrimidine-5-carboxamide

Participants

Role	Name	HCID	Charge
Reactant	1-(3-Aminophenyl)pyrrolidin-2-one	HCID 683956	—
Reactant	2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[4-(1,2-oxazol-5-yl)anilino]pyrimidine-5-carboxamide	HCID 46184612	—
Product	2-((1R,2S)-2-aminocyclohexylamino)-4-(3-(2-oxopyrrolidin-1-yl)phenylamino)pyrimidine-5-carboxamide	HCID 46184366	—

Reaction Steps

This compound was synthesised using the synthetic scheme described for the synthesis of compound 122, and using 1-(3-aminophenyl)pyrrolidin-2-one in step 1. MS: 410.5 (M+H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08318755B2
Source dataset	uspto-grants-2012_11
ORD ID	ord-3c8f41cc3d1344028297d702091ffe58
Source note	uspto-grants-2012_11