4-(3,5-dimethyl-1H-pyrazol-1-yl)aniline → HCID 46184610, compound

HRID 1880299Notes

Reaction equation

HRID 1880299 reaction equation
[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13](NC2C=CC(C3ON=CC=3)=CC=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1.[CH3:30][C:31]1[CH:35]=[C:34]([CH3:36])[N:33]([C:37]2[CH:43]=[CH:42][C:40]([NH2:41])=[CH:39][CH:38]=2)[N:32]=1>>[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13]([NH:41][C:40]2[CH:42]=[CH:43][C:37]([N:33]3[C:34]([CH3:36])=[CH:35][C:31]([CH3:30])=[N:32]3)=[CH:38][CH:39]=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1

Participants

3

Reactant 2

HCID 7145504-(3,5-dimethyl-1H-pyrazol-1-yl)anilineHCID 461846122-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[4-(1,2-oxazol-5-yl)anilino]pyrimidine-5-carboxamide

Product 1

HCID 46184610HCID 46184610, compound

Procedure

This compound was synthesised using the synthetic scheme described for the synthesis of compound 122, and using 4-(3,5-dimethyl-1H-pyrazol-1-yl)aniline in step 1. MS: 421.5 (M+H).

Workup

  1. customThis compound was synthesised

Sources & evidence

ORD record
ord-19793563019f4935878a3bf5466bb646
Source dataset
uspto-grants-2012_11
Patent number
US08318755B2

Reaction notes

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