3-methoxy-5-(1H-tetrazol-1-yl)aniline → HCID 46184135, compound

HRID 1880300Notes

Reaction equation

HRID 1880300 reaction equation
[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13](NC2C=CC(C3ON=CC=3)=CC=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1.[CH3:30][O:31][C:32]1[CH:33]=[C:34]([CH:36]=[C:37]([N:39]2[CH:43]=[N:42][N:41]=[N:40]2)[CH:38]=1)[NH2:35]>>[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13]([NH:35][C:34]2[CH:36]=[C:37]([N:39]3[CH:43]=[N:42][N:41]=[N:40]3)[CH:38]=[C:32]([O:31][CH3:30])[CH:33]=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1

Participants

3

Reactant 2

HCID 49131443-methoxy-5-(1H-tetrazol-1-yl)anilineHCID 461846122-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[4-(1,2-oxazol-5-yl)anilino]pyrimidine-5-carboxamide

Product 1

HCID 46184135HCID 46184135, compound

Procedure

This compound was synthesised using the synthetic scheme described for the synthesis of compound 122, and using 3-methoxy-5-(1H-tetrazol-1-yl)aniline in step 1. MS: 425.4 (M+H).

Workup

  1. customThis compound was synthesised

Sources & evidence

ORD record
ord-b97ecd6e09f8400d825e823f59832827
Source dataset
uspto-grants-2012_11
Patent number
US08318755B2

Reaction notes

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