Acetic Acid → 2-Oxopropanal (3-methoxyphenyl)hydrazone

Participants

Reaction Steps

Acetic acid (1.7 mL) was added to a solution of 3-methoxyphenylhydrazine (3.0 g, 17 mmol) in water (35 mL). This mixture was then added dropwise to a solution of pyruvaldehyde (3.1 g, 2.8 mL, 17 mmol) in water (45 ml) over 15 minutes. The mixture was stirred for two days and solids were removed by filtration and washed with water to obtain 2-oxopropanal (3-methoxyphenyl)hydrazone as a black solid (1.1 g, 33%).

Provenance & Evidence