tert-Butyldimethylsilyl chloride → HCID 59676139, compound

HRID 1880455Notes

Reaction equation

HRID 1880455 reaction equation
[CH3:1][N:2]1[C:14]2[C:13]3[CH:15]=[CH:16][CH:17]=[CH:18][C:12]=3[S:11][CH2:10][C:9]=2[C:8]2[C:3]1=[CH:4][CH:5]=[C:6]([OH:19])[CH:7]=2.[CH3:20][C:21]([Si:24](Cl)([CH3:26])[CH3:25])([CH3:23])[CH3:22]>>[C:21]([Si:24]([CH3:26])([CH3:25])[O:19][C:6]1[CH:7]=[C:8]2[C:3](=[CH:4][CH:5]=1)[N:2]([CH3:1])[C:14]1[C:13]3[CH:15]=[CH:16][CH:17]=[CH:18][C:12]=3[S:11][CH2:10][C:9]2=1)([CH3:23])([CH3:22])[CH3:20]

Participants

3

Reactant 2

HCID 28928tert-Butyldimethylsilyl chlorideHCID 44411867HCID 44411867, compound

Product 1

HCID 59676139HCID 59676139, compound

Procedure

Following the procedure described in Example 80, using 11-methyl-6,11-dihydro-5-thia-11-aza-benzo[a]fluoren-8-ol (1.15 g, 3.123 mmol) and TBSCl (562 mg, 3.75 mmol) as the starting material, the title compound was prepared as a white solid.

Sources & evidence

ORD record
ord-87c5516383f544b58f68ad1a2376778f
Source dataset
uspto-grants-2012_11
Patent number
US08318766B2

Reaction notes

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