HCID 619571, compound → HCID 59676062, compound

HRID 1880467Notes

Reaction equation

HRID 1880467 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:13](=[CH:14][CH:15]=1)[NH:12][C:11]1[C:10]3[CH:16]=[CH:17][CH:18]=[CH:19][C:9]=3[O:8][CH2:7][C:6]2=1.Cl.Cl[CH2:22][C:23]1[CH:38]=[CH:37][C:26]([O:27][CH2:28][CH2:29][NH:30][CH:31]2C[CH2:35][CH2:34][CH2:33][CH2:32]2)=[CH:25][CH:24]=1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:13](=[CH:14][CH:15]=1)[N:12]([CH2:22][C:23]1[CH:24]=[CH:25][C:26]([O:27][CH2:28][CH2:29][N:30]3[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35]3)=[CH:37][CH:38]=1)[C:11]1[C:10]3[CH:16]=[CH:17][CH:18]=[CH:19][C:9]=3[O:8][CH2:7][C:6]2=1

Participants

3

Reactant 2

HCID 619571HCID 619571, compoundHCID 67237209HCID 67237209, compound

Product 1

HCID 59676062HCID 59676062, compound

Procedure

Following the procedure described in Example 102, using 8-methoxy-6,11-dihydro-5-oxa-11-aza-benzo[a]fluorene (150 mg, 0.562 mmol) and [2-(4-chloromethyl-phenoxy)-ethyl]-cyclohexanyl-amine hydrochloride salt as the starting material, the title compound was prepared as a brown solid.

Sources & evidence

ORD record
ord-7991999acfe2488d86150084973143ff
Source dataset
uspto-grants-2012_11
Patent number
US08318766B2

Reaction notes

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