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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1880539Generated: October 29, 2026

Aminoacetonitrile → HCID 86590551, compound

https://huagongshe.com/reaction/1880539

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAminoacetonitrileHCID 10901—
ReactantN-[(S)-(4-Bromophenyl)(2,4-difluorophenyl)methyl]-L-leucineHCID 67298378—
ProductHCID 86590551HCID 86590551—

Reaction Steps

Using the procedure mentioned in the Step 4 of Example 19, (2S)-2-{(S)-[(4-bromophenyl)-(2,4-difluorophenyl)-methyl]-amino}-4-methyl-pentanoic acid was coupled with amino acetonitrile to give (2S)-2-{(S)-[(4-bromophenyl)-(2,4-difluorophenyl)-methyl]-amino}-4-methylpentanoic acid cyanomethylamide as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318748B2
Source datasetuspto-grants-2012_11
ORD IDord-28dcef340de948439e2a356d8ae9f8ca
Source noteuspto-grants-2012_11