HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aminoacetonitrile → HCID 86590554, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aminoacetonitrile | HCID 10901 | — |
| Reactant | HCID 57454787 | HCID 57454787 | — |
| Reactant | HCID 67298406 | HCID 67298406 | — |
| Product | HCID 86590554 | HCID 86590554 | — |
Reaction Steps
N2-[1-(4-Bromophenyl)-2,2,2-trifluoroethyl]-N1-(cyanomethyl)-L-norvalinamide was prepared in similar manner to N1-(1-cyanocyclopropyl)-N2-{(1S)-2,2,2-trifluoro-1-[4′-(methylsulfonyl)-1,1′-biphenyl-4-yl]ethyl}-L-norvalinamide using aminoacetonitrile in the coupling step with (2S)-2-[(S)-1-(4-bromophenyl)-2,2,2-trifluoroethylamino]-pentanoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08318748B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-78b4ba81045343ab82803edc993b0d9c |
| Source note | uspto-grants-2012_11 |