1,8-Diazabicyclo(5.4.0)undec-7-ene → HCID 59570290, compound

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Reaction Steps

To 1 ml of pyridine were added 0.28 g of 1,8-diazabicyclo[5,4,0]undec-7-ene, and 0.3 g of 3-(4-trifluoromethylpyridin-2-yl)-1,2,4-oxadiazol-5-one, and 0.29 g of N,N-diallylcarbamoyl chloride was added at room temperature. After stirring for 8 hours, the resultant solution was concentrated, and the residue was subjected to silica gel column chromatography to obtain 0.34 g of 3-(4-trifluoromethylpyridin-2-yl)-N,N-diallyl-1,2,4-oxadiazol-5-one-4-carboxamide (present compound (17)).

Provenance & Evidence