Acetonitrile → HCID 59570344, compound

Participants

Reaction Steps

To 7 ml of acetonitrile were added 0.7 g of 2-cyclopropyl-4-trifluoromethylpyridine N-oxide, 0.96 ml of triethylamine, and 1 g of trimethylsilyl cyanide, and the mixture was heated to reflux for 20 hours. Thereafter, the reaction solution was allowed to cool to room temperature, and concentrated. The residue was subjected to silica gel column chromatography to obtain 0.6 g of 6-cyclopropyl-4-trifluoromethylpyridine-2-carbonitrile.

Provenance & Evidence