HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-[1-(Trifluoromethyl)ethenyl]pyridine → 4-(2,2,2-Trifluoro-1-methyl-ethyl)pyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-[1-(Trifluoromethyl)ethenyl]pyridine | HCID 59570355 | — |
| Edukt | HCID 178418361 | HCID 178418361 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Ethyl Acetate | HCID 8857 | — |
| Produkt | 4-(2,2,2-Trifluoro-1-methyl-ethyl)pyridine | HCID 59570337 | 85,7% |
Reaktionsschritte
To 20 ml of ethyl acetate were added 1.5 g of 4-[1-(trifluoromethyl)ethenyl]pyridine and 0.15 g of 10% Pd/C, and the mixture was stirred under the hydrogen atmosphere for 7 hours. The mixture was filtered, the filtrate was concentrated, and the residue was subjected to silica gel column chromatography to obtain 1.3 g of 4-(2,2,2-trifluoro-1-methyl-ethyl)pyridine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08318776B2 |
| Quelldatensatz | uspto-grants-2012_11 |
| ORD ID | ord-3931ff0361f24cb786007c5b926220fa |
| Quellennotiz | uspto-grants-2012_11 |