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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1880783Generated: October 31, 2026

[3-Chloro-5-(trifluoromethyl)-2-pyridinyl][(diphenylmethylene)amino]acetonitrile → Amino[3-chloro-5-(trifluoromethyl)-2-pyridinyl]acetonitrile hydrochloride

https://huagongshe.com/reaction/1880783

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[3-Chloro-5-(trifluoromethyl)-2-pyridinyl][(diphenylmethylene)amino]acetonitrileHCID 22988174—
SolventHydrochloric AcidHCID 313—
SolventDichloromethaneHCID 6344—
ProductAmino[3-chloro-5-(trifluoromethyl)-2-pyridinyl]acetonitrile hydrochlorideHCID 23078241—

Reaction Steps

15.0 g of [3-chloro-5-(trifluoromethyl)-2-pyridinyl][(diphenylmethylene)amino]acetonitrile (0.037 mol) are stirred at room temperature for 3 h in a mixture of dichloromethane (15 mL) and hydrochloric acid 10% (15 mL). Phases are separated and the organic phase is washed with 15 mL of hydrochloric acid 10%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318777B2
Source datasetuspto-grants-2012_11
ORD IDord-dd41364ff22d44a1a7c9f402a0d0d5d0
Source noteuspto-grants-2012_11