HCID 22611355, compound → HCID 57955664, compound

Participants

Reaction Steps

The title compound was prepared using Buchwald reaction from 2-Chloro-9-cyclopentyl-7,7-difluoro-5-methyl-8,9-dihydro-5H-pyrimido[5,4-b][1,4]diazepin-6(7H)-one and 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-amine. 1H NMR (400 MHz, DMSO-d6) δ ppm 1.10-1.31 (m, 4 H) 1.65 (m, 8 H) 2.02 (m, 3 H) 2.98 (br. s., 2 H) 3.46 (s, 3 H) 4.02-4.25 (m, 2 H) 4.88 (br. s., 2 H) 6.26 (s, 1 H), 6.65 (d, J=8 Hz, 1 H), 7.10 (s, 1 H), 7.98 (s, 1 H) 8.34 (d, J=8.0 Hz, 1 H) 8.45 (s, 1 H). [M+H] calc'd for C26H29F2N7O, 494; found 494.

Provenance & Evidence