HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1880968Generated: October 30, 2026
Water → 3-Fluoro-5-methoxy-4-nitrobenzoic acid
https://huagongshe.com/reaction/1880968
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 3-Fluoro-5-methoxy-4-nitrobenzonitrile | HCID 57955540 | — |
| Product | 3-Fluoro-5-methoxy-4-nitrobenzoic acid | HCID 57955522 | 75% |
Reaction Steps
A suspension of 3-fluoro-5-methoxy-4-nitrobenzonitrile (940 mg, 4.8 mmol) in a mixture of concentrated H2SO4 and water (2 mL/2 mL) was heated at 100° C. overnight. The reaction mixture was then cooled down, solid filtered and dried to give the product as brown solid (770 mg, 75%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08318727B2 |
|---|
| Source dataset | uspto-grants-2012_11 |
|---|
| ORD ID | ord-9c665369f2f24085a8851d682bd31f57 |
|---|
| Source note | uspto-grants-2012_11 |
|---|
