Acetaldehyde → HCID 57955595, compound

Participants

Reaction Steps

The title compound was synthesized by following the Reductive Amination Procedure using N-(azetidin-3-yl)-4-(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-ylamino)-2-fluoro-5-methoxybenzamide and acetaldehyde. 1H NMR (400 MHz, DMSO-d6) δ ppm 0.87 (t, J=7.20 Hz, 3 H) 1.61 (br. s., 6 H) 1.96 (br. s., 2 H) 2.40 (q, 2 H) 2.88 (t, J=6.32 Hz, 2 H) 3.52 (t, J=5.81 Hz, 2 H) 3.91 (s, 3 H) 4.08 (t, J=13.77 Hz, 2 H) 4.33-4.48 (m, 1 H) 4.71-4.89 (m, 1 H) 7.20 (d, J=4.04 Hz, 1 H) 8.05 (s, 1 H) 8.26 (d, J=13.39 Hz, 1 H) 8.31 (d, J=3.28 Hz, 1 H) 8.43 (d, J=7.07 Hz, 1 H). [M+H] calculated for C26H32F3N7O3, 548; found 548.

Provenance & Evidence