HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(4-Methoxyphenyl)-5-oxopentanoic acid → 5-(4-Methoxyphenyl)pentanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(4-Methoxyphenyl)-5-oxopentanoic acid | HCID 266817 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | HCID 178418361 | HCID 178418361 | — |
| Product | 5-(4-Methoxyphenyl)pentanoic acid | HCID 344501 | 99.3% |
Reaction Steps
5-(4-methoxyphenyl)-5-oxopentanoic acid (8) (11.5 g) from the previous step was dissolved in ethyl alcohol (150 mL) and acetic acid (50 mL), 10% palladium-activated carbon (1.2 g) was added, then stirred overnight in hydrogen atmosphere at room temperature. After filtration and vacuum concentration, the above-identified compound was obtained as a colorless solid (10.7 g, yield 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08318781B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-83bf6ed1cc98472680800b254f355b74 |
| Source note | uspto-grants-2012_11 |