HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorophenethyl iodide → HCID 178460753, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorophenethyl iodide | HCID 22314719 | — |
| Reactant | Ethyl 2-[(2-amino-1,3-thiazol-5-yl)sulfanyl]-2-methylpropanoate | HCID 57481427 | — |
| Reactant | HCID 178460750 | HCID 178460750 | — |
| Product | HCID 178460753 | HCID 178460753 | — |
Reaction Steps
The compound was prepared following an analogous procedure to the one described for the synthesis of 2-Methyl-2-{2-[3-(trans-4-methyl-cyclohexyl)-3-phenethyl -ureido]-thiazol-5-ylsulfanyl}-propionic acid using 1-chloro-4-(2-iodo-ethyl)-benzene (J. Med. Chem. 1998, 41,3, 358-378) and 2-(2-amino-thiazol-5-ylsulfanyl)-2-methyl-propionic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08318778B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-e209680c34824a2084a3057f09f1aea0 |
| Source note | uspto-grants-2012_11 |