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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1881076Generated: November 2, 2026

1-(Bromomethyl)-2-(trifluoromethyl)benzene → HCID 178454944, compound

https://huagongshe.com/reaction/1881076

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)-2-(trifluoromethyl)benzeneHCID 123057—
Reactant3-(2-Amino-thiazol-5-ylsulfanyl)-2,2-dimethyl-propionic acid ethyl esterHCID 57481429—
ReactantHCID 178454946HCID 178454946—
ProductHCID 178454944HCID 178454944—

Reaction Steps

The compound was prepared following an analogous procedure to the one described for the synthesis of 3-{2-[3-[2-(2-Chloro-benzyloxy)-ethyl]-3-(trans-4-methyl -cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-2,2-dimethyl-propionic acid using 3-(2-amino-thiazol -5-ylsulfanyl)-2,2-dimethyl-propionic acid ethyl ester and 2-trifluoromethylbenzyl bromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318778B2
Source datasetuspto-grants-2012_11
ORD IDord-3a44ce0bb9114d60b344aac0fbfe7d36
Source noteuspto-grants-2012_11