HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(p-Methoxyphenyl)propionic acid → {2-[-3-[3-(4-Methoxy-phenyl)-propyl]-3-(4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(p-Methoxyphenyl)propionic acid | HCID 95750 | — |
| Reactant | Ethyl 2-(2-aminothiazol-5-ylthio)acetate | HCID 21455623 | — |
| Reactant | HCID 178461316 | HCID 178461316 | — |
| Product | {2-[-3-[3-(4-Methoxy-phenyl)-propyl]-3-(4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid | HCID 59192493 | — |
Reaction Steps
The compound was prepared following an analogous procedure to the one described for the synthesis of {2-[-3-[3-(3-chloro-phenyl)-propyl]-3-(trans-4-methyl -cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid using 3-(4-methoxy-phenyl)-propionic acid and (2-aminothiazol-5-ylsulfanyl) acetic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08318778B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-b037c51560df434481ddf0d4bd83f734 |
| Source note | uspto-grants-2012_11 |