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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1881095Generated: November 1, 2026

3-(3-Trifluoromethylphenyl)propanoic acid → HCID 178461314, compound

https://huagongshe.com/reaction/1881095

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-Trifluoromethylphenyl)propanoic acidHCID 2777683—
ReactantEthyl 2-(2-aminothiazol-5-ylthio)acetateHCID 21455623—
ReactantHCID 178461316HCID 178461316—
ProductHCID 178461314HCID 178461314—

Reaction Steps

The compound was prepared following an analogous procedure to the one described for the synthesis of {2-[-3-[3-(3-Chloro-phenyl)-propyl]-3-(trans-4-methyl -cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid using 3-(3-trifluoromethyl-phenyl) -propionic acid and (2-aminothiazol-5-ylsulfanyl) acetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318778B2
Source datasetuspto-grants-2012_11
ORD IDord-ac5d13e46e5c4f5cb735bd28d42a9013
Source noteuspto-grants-2012_11