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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1881136Generated: November 2, 2026

5-(2-Bromoethyl)-2,3-dihydro-1-benzofuran → HCID 178460748, compound

https://huagongshe.com/reaction/1881136

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(2-Bromoethyl)-2,3-dihydro-1-benzofuranHCID 21831160—
ReactantEthyl 2-[(2-amino-1,3-thiazol-5-yl)sulfanyl]-2-methylpropanoateHCID 57481427—
ReactantHCID 178460750HCID 178460750—
ProductHCID 178460748HCID 178460748—

Reaction Steps

The compound was prepared following an analogous procedure to the one described for the synthesis of 2-methyl-2-{2-[3-(trans-4-methyl-cyclohexyl)-3-phenethyl -ureido]-thiazol-5-ylsulfanyl}-propionic acid using 5-(2-bromo-ethyl)-2,3-dihydro-benzofuran and 2-(2-amino-thiazol-5-ylsulfanyl)-2-methyl-propionic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318778B2
Source datasetuspto-grants-2012_11
ORD IDord-60dfdba436c14aeeaa9edd2c125a50fb
Source noteuspto-grants-2012_11