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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1881143Generated: November 3, 2026

3-(Bromomethyl)-5-chloro-1-benzothiophene → HCID 178461343, compound

https://huagongshe.com/reaction/1881143

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Bromomethyl)-5-chloro-1-benzothiopheneHCID 2779857—
ReactantEthyl 2-(2-aminothiazol-5-ylthio)acetateHCID 21455623—
ReactantHCID 178454946HCID 178454946—
ProductHCID 178461343HCID 178461343—

Reaction Steps

The compound was prepared following an analogous procedure to the one described for the synthesis of 3-{2-[3-[2-(2-chloro-benzyloxy)-ethyl]-3-(trans-4-methyl -cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-2,2-dimethyl-propionic acid using 3-bromomethyl-5-chloro-benzo[b]thiophene and (2-aminothiazol-5-ylsulfanyl) acetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318778B2
Source datasetuspto-grants-2012_11
ORD IDord-5abed2e7211c4e96bd4bc11cc05093ee
Source noteuspto-grants-2012_11