Boron tribromide → HCID 67094346, compound

HRID 1881153Notes

Reaction equation

HRID 1881153 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:16][C:15]3[C:10](=[CH:11][C:12]([O:19]C)=[C:13]([O:17]C)[CH:14]=3)[C:9]2=[O:21])=[CH:4][CH:3]=1.B(Br)(Br)Br>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:16][C:15]3[C:10](=[CH:11][C:12]([OH:19])=[C:13]([OH:17])[CH:14]=3)[C:9]2=[O:21])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 25134Boron tribromideHCID 67094269HCID 67094269, compound

Product 1

HCID 67094346HCID 67094346, compound

Procedure

2-(4-Chloro-phenyl)-5,6-dimethoxy-2,3-dihydro-isoindol-1-one (0.74 g) was demethylated with 4 eq of boron tribromide as described in Example 8.

Sources & evidence

ORD record
ord-b8413dd3251e4ad5b08c99575774fc1f
Source dataset
uspto-grants-2012_11
Patent number
US08318785B2

Reaction notes

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