HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → 5,6-Dihydroxy-7-nitro-2-benzofuran-1(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | 5,6-Dihydroxyisobenzofuran-1(3H)-one | HCID 20622260 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 5,6-Dihydroxy-7-nitro-2-benzofuran-1(3H)-one | HCID 15982841 | — |
Reaction Steps
To a solution of 5,6-dihydroxy-3H-isobenzofuran-1-one (0.4 g) in sulfuric acid at −30° C. was added 5 M nitric acid in sulfuric acid (0.55 ml). The reaction mixture was let to warm up to room temperature and then poured into ice water. The product was filtered and recrystallized from acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08318785B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-8ce25539c24c41c6bc6bc1c8e4e39b7f |
| Source note | uspto-grants-2012_11 |