Hydrochloric Acid → 3',4'-Dimethoxycinnamic acid

Participants

Reaction Steps

3,4-Dimethoxybenzaldehyde (5 g), malonic acid (4.7 g), piperidine (0.5 ml) and pyridine (15 ml) were refluxed for six hours. The reaction mixture was poured into ice-cold water and acidified with 6M hydrochloric acid. The resultant solid was filtered, washed with water and dried under vacuum.

Provenance & Evidence