Hydrochloric Acid → 5-Ethoxy-4-hydroxy-2-nitrobenzaldehyde

Participants

Reaction Steps

4-Benzyloxy-5-ethoxy-2-nitro-benzaldehyde (23 g) was dissolved in acetic acid (93 ml) and concentrated hydrochloric acid (10 ml). The reaction solution was refluxed for 24 hours. Then the solution was evaporated to dryness and the residue was dissolved in diethyl ether. The product was extracted into 1M sodium hydroxide and acidified with 6M hydrochloric acid. The resultant solid was filtered and dried under vacuum.

Provenance & Evidence