Nitric Acid → HCID 15983107, compound

Participants

Reaction Steps

(5,6-Dihydroxy-3-methylbenzo[b]thiophen-2-yl)morpholin-4-yl-methanone (0.10 g) was dissolved to ethyl acetate (60 ml). Nitric acid (2 eq, 2 M solution in dichloromethane) was added in small portions at 55° C. 15 minutes after last addition the mixture was cooled, washed with water, dried with Na2SO4 and concentrated to small volume. The precipitated product was filtered.

Provenance & Evidence