Methanol → HCID 15983356, compound

Participants

Reaction Steps

A solution of 1 N boron tribromide in dichloromethane (3.4 ml) was added to a solution of 5,6-di(ethoxy-3-methyl-2-(morpholine-4-carbonyl)-benzo[b]thiophene-4-carbonitrile (0.19 g) in dichloromethane (40 ml) at 0° C. The mixture was allowed to stay at 6° C. for two days. Methanol was added and the mixture was evaporated to dryness. To the residue 0.1 N HCl was added and the product was extracted into ethyl acetate. Ethyl acetate was dried and evaporated to dryness. The compound was recrystallized from isopropanol.

Provenance & Evidence