2-Fluoroethyl bromide → Benzyl 3-[(3,6-diethylpyrazin-2-yl)amino]-4-(2-fluoroethoxy)pyrrolidine-1-carboxylate

HRID 188128Notes

Reaction equation

HRID 188128 reaction equation
[CH2:32]([CH3:33])[c:34]1[c:35]([NH:42][CH:43]2[CH2:44][N:45]([C:49](=[O:50])[O:51][CH2:52][c:53]3[cH:54][cH:55][cH:56][cH:57][cH:58]3)[CH2:46][CH:47]2[OH:48])[n:36][c:37]([CH2:40][CH3:41])[cH:38][n:39]1.[Cl:1][c:2]1[cH:3][c:4]([Cl:5])[cH:6][cH:7][c:8]1-[c:9]1[n:10][c:11]([CH2:12][CH3:13])[c:14]([NH:15][CH:16]2[c:17]3[c:18]([cH:19][cH:20][cH:21][cH:22]3)[CH2:23][CH:24]2[O:25][CH2:26][CH3:27])[n:28][c:29]1[CH2:30][CH3:31].[F:59][CH2:60][CH2:61][Br:62]>>[CH2:32]([CH3:33])[c:34]1[c:35]([NH:42][CH:43]2[CH2:44][N:45]([C:49](=[O:50])[O:51][CH2:52][c:53]3[cH:54][cH:55][cH:56][cH:57][cH:58]3)[CH2:46][CH:47]2[O:48][CH2:61][CH2:60][F:59])[n:36][c:37]([CH2:40][CH3:41])[cH:38][n:39]1

Participants

4

Reactant 3

HCID 129822-Fluoroethyl bromideHCID 22147241Benzyl 3-[(3,6-diethylpyrazin-2-yl)amino]-4-hydroxypyrrolidine-1-carboxylateHCID 221473105-(2,4-dichlorophenyl)-N-(2-ethoxy-2,3-dihydro-1H-inden-1-yl)-3,6-diethylpyrazin-2-amine

Product 1

HCID 22147388Benzyl 3-[(3,6-diethylpyrazin-2-yl)amino]-4-(2-fluoroethoxy)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-cd90cb187ffa4438acb035289a19672d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…