Dichloromethane → 3-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-5-bromophenol

HRID 188141Notes

Reaction equation

HRID 188141 reaction equation
[B:23]([Br:24])([Br:25])[Br:26].[Br:1][c:2]1[cH:3][c:4](-[c:10]2[n:11][n:12]([CH:20]([CH3:21])[CH3:22])[c:13]3[n:14][cH:15][n:16][c:17]([NH2:19])[c:18]23)[cH:5][c:6]([O:8][CH3:9])[cH:7]1.[Cl:27][CH2:28][Cl:29]>>[Br:1][c:2]1[cH:3][c:4](-[c:10]2[n:11][n:12]([CH:20]([CH3:21])[CH3:22])[c:13]3[n:14][cH:15][n:16][c:17]([NH2:19])[c:18]23)[cH:5][c:6]([OH:8])[cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 25134Boron tribromideHCID 249051843-(3-bromo-5-methoxyphenyl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Product 1

HCID 249051863-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-5-bromophenol

Sources & evidence

ORD record
ord-c32b5b17003b499b8489a7496b05b7e1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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