反应详情

温度

100 °C

2-Oxopropanal methylhydrazone (8.6 mmol, 861 mg) synthesized in Reference Synthetic Example 1 and (4-n-pentylphenyl)(oxo)acetaldehyde (8.6 mmol, 1.757 g) synthesized in Reference Synthetic Example 6 were dissolved in acetic acid (30 mL) and stirred at 100° C. for about 5 hours. Then, the solvent was evaporated, and the residue was dried by means of a vacuum pump and purified by silica gel column chromatography (n-hexane/AcOEt=2/1, and 4/1) to give the desired product as an orange solid (252.5 mg, yield 10.3%, crude).

1. customsynthesized in Reference Synthetic Example 6
2. customThen, the solvent was evaporated
3. customthe residue was dried by means of a vacuum pump
4. custompurified by silica gel column chromatography (n-hexane/AcOEt=2/1, and 4/1)