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2-(4-t-Butylphenyl)-3-hydroxy-4-methylcarbonylthiophene → Methyl 2-bromo-4-[(2-{1-[5-(4-t-butylphenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)carbonyl]benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(4-t-Butylphenyl)-3-hydroxy-4-methylcarbonylthiophene | HCID 44207289 | — |
| 反応物 | Methyl 2-bromo-4-hydrazinocarbonylbenzoate | HCID 67050217 | — |
| 生成物 | Methyl 2-bromo-4-[(2-{1-[5-(4-t-butylphenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)carbonyl]benzoate | HCID 72360105 | — |
反応手順
Using 2-(4-t-butylphenyl)-3-hydroxy-4-methylcarbonylthiophene (55 mg, 0.20 mmol) and methyl 2-bromo-4-hydrazinocarbonylbenzoate (60 mg, 0.22 mmol) as the starting materials, the desired product was obtained in the same manner as in Synthetic Example 65 as a yellow solid (92 mg, yield 87%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08318796B2 |
| 出典データセット | uspto-grants-2012_11 |
| ORD ID | ord-5431ad90f806487995d561e70a30ab58 |
| 出典メモ | uspto-grants-2012_11 |