HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-t-Butylphenyl)-3-hydroxy-4-methylcarbonylthiophene → Methyl 2-chloro-4-[(2-{1-[5-(4-t-butylphenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)carbonyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-t-Butylphenyl)-3-hydroxy-4-methylcarbonylthiophene | HCID 44207289 | — |
| Reactant | Methyl 2-chloro-4-hydrazinocarbonylbenzoate | HCID 67050317 | — |
| Product | Methyl 2-chloro-4-[(2-{1-[5-(4-t-butylphenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)carbonyl]benzoate | HCID 72360019 | — |
Reaction Steps
Using 2-(4-t-butylphenyl)-3-hydroxy-4-methylcarbonylthiophene (55 mg, 0.20 mmol) and methyl 2-chloro-4-hydrazinocarbonylbenzoate (50 mg, 0.22 mmol) as the starting materials, the desired product was obtained in the same manner as in Synthetic Example 65 as a pale yellow solid (86 mg, yield 89%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08318796B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-ee7f14c875b94423acbab11f46131c6b |
| Source note | uspto-grants-2012_11 |