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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1881643Generated: November 3, 2026

1-[5-(4-t-Butylphenyl)-4-hydroxy-1-methyl-1H-pyrazol-3-yl]ethanone → 5-{[(2-{1-[5-(4-t-butylphenyl)-4-hydroxy-1-methyl-1H-pyrazol-3-yl]ethylidene}hydrazino)-carbonothioyl]amino}-2-thiophenecarboxylic acid

https://huagongshe.com/reaction/1881643

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[5-(4-t-Butylphenyl)-4-hydroxy-1-methyl-1H-pyrazol-3-yl]ethanoneHCID 67050084—
Reactant5-Hydrazinocabonothioylamino-2-thiophenecarboxylic acidHCID 86014497—
Product5-{[(2-{1-[5-(4-t-butylphenyl)-4-hydroxy-1-methyl-1H-pyrazol-3-yl]ethylidene}hydrazino)-carbonothioyl]amino}-2-thiophenecarboxylic acidHCID 72360108—

Reaction Steps

From 1-[5-(4-t-butylphenyl)-4-hydroxy-1-methyl-1H-pyrazol-3-yl]ethanone (40.0 mg, 0.15 mmol) and 5-hydrazinocabonothioylamino-2-thiophenecarboxylic acid (35.5 mg, 0.15 mmol), the desired product was obtained in the same manner as in Synthetic Example 2 as a yellow solid (57.3 mg, yield 83%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318796B2
Source datasetuspto-grants-2012_11
ORD IDord-213e924213154d9e90a1739e8a4099a9
Source noteuspto-grants-2012_11